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CONTACT INFORMATION

Department of Pharmacology,
Physiology & Neuroscience
USC School of Medicine
6439 Garners Ferry Road
VA Building 1, Third Floor
Columbia, SC 29208
(For packages, use 29209)
Phone: 803-733-3254
Fax: 803-733-1523

Office of the Dean:
803-733-3200

Fourth PPN Chair Candidate to Visit SOM

The  Pharmacology, Physiology and Neuroscience (PPN) Chair Search Committee is delighted to announce the upcoming visit of their fourth candidate, Mohan K. Raizada, Ph.D., Distinguished Professor in the Department of Physiology and Functional Genomics at the University of Florida College of Medicine.
Dr. Raizada, who will visit the School of Medicine on September 3rd, 4th, and 5th, is a graduate of the University of Lucknow, India who received his Ph.D. from the University of Kanpur, India.  He was previously on the faculty of the Department of Physiology and Biophysics at the University of Iowa before joining the Department of Physiology at the University of Florida in 1981.

  Dr. Raizada’s Research Interests

Elucidation of the Cellular and Molecular Mechanisms Involved in the Brain Angiotensin Control of Cardiovascular Functions:

Our studies have established that the brain Renin-Angiotensin System (RAS) is key in the control of blood pressure and other cardiovascular functions. This view is further supported by the fact that the expression and activity of this system is enhanced in hypertension. Our laboratory has been involved in elucidating the cellular and molecular mechanisms of the brain Ang-II action in the brain in order to develop a better therapeutic strategy for its hyperactivity and thus devise novel ways to control hypertension.

Genetic Targeting of the RAS for the Control of Hypertension:

Our previous studies have established that a single intracardiac injection of a retroviral vector containing either AT1 receptor antisense cDNA or ACE-antisense cDNA prevents animals from developing hypertension for life. This is an exciting observation and provides conceptual support that antisense targeting of the RAS could be an important strategy for the long-term control of hypertension.

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