Research focus groups

Understanding and Treating Neurological and Neuropsychiatric Diseases

Anxiety, Depression, & Stress Disorders

• Gender & drugs on anxiety behavior: MA Wilson
• Chronic Stress, depression and cognition: LP Reagan
• Neurochemistry of stress responses: JR Fadel, LP Reagan, MA Wilson
• Mitochondrial stress and protein modifications:  N Frizzell, J Baynes
• The amygdala fear circuit: AJ McDonald, MA Wilson, JR Fadel, LP Reagan, J Muller
• Hippocampal dysregulation in depression: LP Reagan, CA Grillo
• Glucocorticoid receptor mechanisms: P Housley
• Individual differences in stress responses and cardiovascular disease: S Wood, MA Wilson
• Neuroanatomy of emotional brain centers: AJ McDonald

Epilepsy & Seizure Disorders

• GABAA Receptor modulators in seizure disorders:J Fisher
• Glutamate receptors in epileptogenesis:D Mott
• Functional properties of GABAA and glutamate receptors:  J Fisher; D Mott
• Anxiety-related changes in seizure disorders: D Mott, MA Wilson
• Novel GABAA receptor modulators: J Fisher, D Mott

Complications of Diabetes, Obesity and Metabolic Disorders

• Protein modifications in diabetes: N Frizzell, J Baynes
• Neural basis for the co-morbidity of obesity and depression: LP Reagan, CA Grillo
• Hippocampal dysfunction in metabolic syndrome: LP Reagan
• Homeostatic changes in aging: JR Fadel
• Hypothalamus and homeostasis: J Fadel, LP Reagan, CA Grillo

Disorders of Cognition and Aging

• Basal forebrain cholinergic system in aging-related deficits: JR Fadel
• Cyclic nucleotide signaling in neurocognitive deficits: MP Kelly
• Novel therapeutic targets for schizophrenia and bipolar disease: MP Kelly
• Cognitive deficits in depression and diabetes:  LP Reagan, CA Grillo
• Prefrontal cortex and cognition: JR Fadel
  Protein modifications and mitochondrial stress in Parkinson’s disease: N Frizzell
  Amygdalar neuroanatomy and cognition: AJ McDonald

Stress, Cardiovascular Control & Nociception

• Development of pain mechanisms: SM Sweitzer
• Nociception and cardiovascular control: LB Wilson
• Cell-based screening assays for drug discovery: K Walsh 
• Cardiovascular changes in depression: S Wood
• Insular cortex, sensory integration and perception: JR Augustine

Alcohol and Drugs of Abuse

• Biomarkers of anxiety and alcohol consumption: MA Wilson, JR Fadel
• Fetal Alcohol Syndrome: SJ Kelly
• Epigenetic changes in alcohol consumption disorders:SJ Kelly